Ψ KLKB1 - Balaena mysticetus
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_EZI21C | Balaena mysticetus | LOF (frameshift, premature stop, ss) | Full | No | Genomic & Transcriptomic |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Functional | "Both F12 and KLKB1 participate in the kinin-kallikrein system, with known roles in inflammation, blood pressure control, coagulation and pain." | 10.1016/j.celrep.2014.12.008 |
| Mutation Description | "A related serine protease gene, KLKB1, has also been pseudogenized in a common ancestor to both whales, and is not found in dolphins." | 10.1016/j.celrep.2014.12.008 |
Curator Observations
See supplementary material for details.