| Functional |
"(...) functions cyclic nucleotide-gated channel alpha 2 (CNGA2) and cyclic nucleotide-gated channel alpha 4 (CNGA 4) . These loci encode subunits of the olfactory cyclic nucleotide-gated (CNG) channel that is critical for depolarizing OR neurons and initiating action potentials that are sent to the brain (Michalakis et al.,2006; Nache et al., 2016)." |
10.1016/j.ympev.2017.01.020 |
| Mutation Description |
"P. macrocephalus exhibits multiple inactivating mutations including a 1-bp frameshift insertion in exon 3 , a frameshift deletion that spans the 3´ end of intron 4 (including splice site) plus the first 5-bp of exon 5,and frameshift deletions of 58bp, 79bp, 2bp, and 34bp in exon 6." |
10.1016/j.ympev.2017.01.020 |
| Phenotypic |
"Our results favor the echolocation-priority hypothesis for the evolution of OMP in odontocetes, and further suggest that two other olfactory-specific genes, CNGA2 and CNGA4, are inactivatedin some odontocetes." |
10.1016/j.ympev.2017.01.020 |