Ψ PON1 - Orcinus orca
Reference Gene:
Job_ID:
Curator:
GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
---|---|---|---|---|---|---|
GL_DRNKS6 | Orcinus orca | LOF (frameshift, premature stop, ss) | Full | No | Genomic |
Statements
Type | Excerpt | DOI |
---|---|---|
Functional | "Rewiring of either lipid metabolism or antioxidant networks in ancient marine mammals may have obviated the function of PON1." | 10.1126/science.aap7714 |
Timing of Loss | "This suggests that PON1 lost functional constraint in the ancestral cetacean lineage soon after its split with the ancestral hippopotamid lineage, approximately 53 million years (Ma) ago." | 10.1126/science.aap7714 |