Ψ PON1 - Orcinus orca

Reference Gene:
Job_ID:
Curator:
GlossID Species Gene Loss Mechanism Loss Type Lineage Specific Evidence Accession Nr.
GL_DRNKS6 Orcinus orca LOF (frameshift, premature stop, ss) Full No Genomic

Statements

Type Excerpt DOI
Functional "Rewiring of either lipid metabolism or antioxidant networks in ancient marine mammals may have obviated the function of PON1." 10.1126/science.aap7714
Timing of Loss "This suggests that PON1 lost functional constraint in the ancestral cetacean lineage soon after its split with the ancestral hippopotamid lineage, approximately 53 million years (Ma) ago." 10.1126/science.aap7714