Ψ MTNR1B - Trichechus manatus
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_DQYBFD | Trichechus manatus | LOF (frameshift, premature stop, ss) | Full | Yes | Single individual SRA |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Mutation Description | " In Mtnr1a, a single nucleotide deletion was identified at the exon 2 and a set of frameshift mutations including a premature stop codon were identified in the exon 2 of Mtnr1b. The identified mutations were further validated by SRAs (Figures S26–S29)." | 10.3390/genes10020121 |
| Phenotypic | "Convergent disruption of this set of genes was also observed in T. manatus latirostris. These evidence support the anatomical observations that the pineal gland is absent or vestigial and that classical melatonin-based circadian rhythmicity is lacking in these fully aquatic species [16,17]." | 10.3390/genes10020121 |
Curator Observations
Also reported in : M Huelsmann. 2019 [PMID:31579821].