Ψ AWAT1 - Sus scrofa

Reference Gene:
Job_ID:
Curator:
GlossID Species Gene Loss Mechanism Loss Type Lineage Specific Evidence Accession Nr.
GL_CZ9QH1 Sus scrofa LOF (frameshift, premature stop, ss) Full Yes Multiple individual SRA

Statements

Type Excerpt DOI
Mutation Description "Notably, the presence of ORF disruptive mutations in Mogat3 in all analyzed species (fig. 3C), deleterious mutations in S. scrofa and C. s. simum Awat1 (fig. 3D) and in S. scrofa, L. africana and T. m. latirostris Awat2 (fig. 3D) and in both Dgat2l6 and Fabp9 from C. simum (fig. 3C and F). With the exception of a shared stop codon in the exon 6 of Awat1, all other mutations are not conserved between these species/lineages (fig. 3C and D; supplementary material 3, Supplementary Material online)." 10.1093/molbev/msz068
Phenotypic "In conclusion, our study supports convergent gene loss events in key molecular components responsible for skin sebum production in lineages reported to lack functioning SGs (Sebaceous Glands)." 10.1093/molbev/msz068