| Functional |
"PGLYRP1/3/4 encode peptidoglycan recognition proteins, which are receptors important for antimicrobial function and for maintaining a healthy gut microbiome (75, 76)." |
10.1126/sciadv.aaw6671 |
| Timing of Loss |
"The deletion of the last two exons has shared deletion breakpoints in all species (except the sperm whale, where no alignment chain spans this region), consistent with a gene loss in the cetacean stem lineage." |
10.1126/sciadv.aaw6671 |
| Other |
"Furthermore, while mammals generally have four genes encoding peptidoglycan recognition proteins, which are receptors important for antimicrobial function and for maintaining a healthy gut microbiome, cetaceans have lost three of these four genes (PGLYRP1/3/4; figs. S17 to S19 and table S2)." |
10.1126/sciadv.aaw6671 |