Ψ MTNR1B - Nannospalax galili

Reference Gene:
Job_ID:
Curator:
GlossID Species Gene Loss Mechanism Loss Type Lineage Specific Evidence Accession Nr.
GL_7PUPJH Nannospalax galili LOF (frameshift, premature stop, ss) Full No Multiple individual SRA XM_008837748.1 

Statements

Type Excerpt DOI
Functional "In mammals, Mtnr1a and Mtnr1b receptors are involved in the response of the clock machinery to melatonin stimulation (Reppart et al. 1996)." 10.1007/s00239-021-10025-1
Mutation Description "Other species with ORF-disruptive mutations include Nannospalax galili (northern Israeliblind subter ranean mole rat), exhibiting a single nucleotide deletion in exon 1, D. dugon with a conserved fourteen-nucleotide dele tion in exon 2 or G. variegatus with an indel also in exon 1 (Online Resources 4 and 13)." 10.1007/s00239-021-10025-1
Methodology & Validation "Mutational validation was performed through retrieval of raw sequencing reads in (at least) two independent Sequence Read Archive (SRA) projects (when available)." 10.1007/s00239-021-10025-1

Curator Observations

Consult Supplementary Data 4 and 13.