Ψ PGLYRP1 - Orcinus orca
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_735PRK | Orcinus orca | LOF (frameshift, premature stop, ss) | Full | Yes | Single individual SRA | XM_004271143.3 |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Functional | "PGLYRP1/3/4 encode peptidoglycan recognition proteins, which are receptors important for antimicrobial function and for maintaining a healthy gut microbiome (75, 76)." | 10.1126/sciadv.aaw6671 |
| Other | "Furthermore, while mammals generally have four genes encoding peptidoglycan recognition proteins, which are receptors important for antimicrobial function and for maintaining a healthy gut microbiome, cetaceans have lost three of these four genes (PGLYRP1/3/4; figs. S17 to S19 and table S2)." | 10.1126/sciadv.aaw6671 |
Curator Observations
See reference supplementary material.