Ψ TLR5 - Arctocephalus gazella
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_6E6IYX | Arctocephalus gazella | LOF (frameshift, premature stop, ss) | Full | Yes | Genomic |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Mutation Description | "Analyzing TLR5 in the Antarctic fur seal, we found that the 1, 25 and 17 bp frameshifting deletions are shared between both fur seals (grey background). In addition, the Antarctic fur seal exhibits several lineage-specific mutations." | 10.1093/molbev/msaa058 |
| Timing of Loss | "Together, the presence of inactivating mutations shared between Otariidae, Phocidae, and Odobenidae suggests that TLR5 loss already occurred in the pinniped stem lineage at least aprox.26Ma (the estimated split of pinnipeds according to TimeTree." | 10.1093/molbev/msaa058 |