Ψ TLR5 - Cavia porcellus
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_3O1UZW | Cavia porcellus | LOF (frameshift, premature stop, ss) | Full | Yes | Genomic & Transcriptomic |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Mutation Description | "In contrast to these nine species, all frameshifts and stop codon mutations present in the domestic guinea pig, Weddell seal, and Pacific walrus were confirmed by several sequencing reads and we found no support for the ancestral, noninactivating allele (fig. 1A, supplementary table 2, Supplementary Material online)." | 10.1093/molbev/msaa058 |
| Timing of Loss | "As shown in figure 1A, both stop codons and the 2 bp deletion are shared between all three guinea pig species. Additionally, the large deletion that removes most of the TLR5 coding exon has the same breakpoints in all three guinea pig species." | 10.1093/molbev/msaa058 |