Ψ AWAT1 - Manis pentadactyla
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_10QJU4 | Manis pentadactyla | LOF (frameshift, premature stop, ss) | Full | Yes | Multiple individual SRA | XM_057495354.1 |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Timing of Loss | "a conserved premature stop codon in the sixth exon in M. javanica, M. pentadactyla, and P. tricuspis [...] Other mutations, including nucleotide deletions and premature stop codons, were also retrieved, notably a set of mutations conserved within the Manis genus" | 10.1007/s00239-023-10118-z |
| Phenotypic | "Ancestral (i.e., Awat1, Awat2, Aadacl3) and independent (i.e., Dgat2l6) pseudogenization events in genes associated with epidermal lipids and sebum production strongly suggest a progressive impairment of the sebum-producing molecular machinery in pangolin lineages." | 10.1007/s00239-023-10118-z |