Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| POLM DNA polymerase mu | Tdt-N , Pol Mu | Homo sapiens | 11 | protein-coding | POLB , DNTT , POLL | 2.7.7.7 | 606344 |
Summary
Predicted to enable DNA-directed DNA polymerase activity. Predicted to be involved in double-strand break repair via nonhomologous end joining. Predicted to act upstream of or within B cell differentiation and somatic hypermutation of immunoglobulin genes. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
GeneOntology
Gene Loss events - POLM (4 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_21OXRF | Orcinus orca | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | Cetacea | 10.1126/sciadv.aaw6671 |
| GL_RGJEEH | Balaenoptera acutorostrata | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | Cetacea | 10.1126/sciadv.aaw6671 |
| GL_S0IED0 | Tursiops truncatus | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | Cetacea | 10.1126/sciadv.aaw6671 |
| GL_SR9IJA | Physeter catodon | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | Cetacea | 10.1126/sciadv.aaw6671 |