Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| GRK7 G protein-coupled receptor kinase 7 | GPRK7 | Homo sapiens | 7 | protein-coding | RSKR , GRK1 , GRK6 , GRK4 , GRK5 , GRK2 , GRK3 | 2.7.11.14 | 606987 |
Summary
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. It is specifically expressed in the retina and the encoded protein has been shown to phosphorylate cone opsins and initiate their deactivation. [provided by RefSeq, Jul 2008]
GeneOntology
Gene Loss events - GRK7 (20 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_0NUQD1 | Nannospalax galili | Rodentia | Gene deletion | Full | No | 10.1093/icb/icy004 |
| GL_18DBFU | Fukomys damarensis | Rodentia | LOF (frameshift, premature stop, ss) | Full | No | 10.1093/icb/icy004 |
| GL_2HCNPN | Hipposideros armiger | Chiroptera | LOF (frameshift, premature stop, ss) | Full | No | 10.1093/icb/icy004 |
| GL_B5WAHO | Mus musculus | Rodentia | Gene deletion | Full | No | 10.1093/icb/icy004 |
| GL_BVRXOH | Balaenoptera edeni | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | 10.1093/molbev/msaa070 | |
| GL_ETDCVA | Dasypus novemcinctus | Cingulata | Gene deletion | Full | No | 10.1093/icb/icy004 |
| GL_FGFUTE | Mesoplodon densirostris | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | 10.1093/molbev/msaa070 | |
| GL_KLD5QV | Caperea marginata | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | No | 10.1093/molbev/msaa070 |
| GL_KYEKJK | Echinops telfairi | LOF (frameshift, premature stop, ss) | Full | No | 10.1093/icb/icy004 | |
| GL_L53VWL | Mesoplodon ginkgodens | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | 10.1093/molbev/msaa070 |