| Functional |
"The protein product of GRK7 phosphorylates cone opsins in many mammalian species, and there is evidence of species-specific expression differences of GRK7 in cones (Liu et al. 2005)." |
10.1093/molbev/msaa070 |
| Mutation Description |
"Putative GRK7 and GUCY2F pseudogenes are found within species of Ziphiidae, Kogiidae, Mysticeti, and Pontoporiidae (table 1)." |
10.1093/molbev/msaa070 |
| Phenotypic |
"The loss of function in GRK7 and other cone-specific genes identified here (OPN1LW, CNGB3, CNGA3, GNAT2, PDE6C) indicates that many more cetacean species have lost cone-mediated vision..." |
10.1093/molbev/msaa070 |
| Other |
"Other mammals, many of which are active in dim-light environments, such as mice and subterranean rodents, goldenmoles, xenarthrans, some bats, and tenrecs, also have lost GRK7 (Weiss et al. 2001; Emerling and Springer 2014, 2015; Fang et al. 2014; Hudson et al. 2014; Emerling 2018)." |
10.1093/molbev/msaa070 |