Reference Gene

Gene name Alias Species Exons Type Paralogs EC number OMIM
TYMP thymidine phosphorylase TP , ECGF , ECGF1 , MNGIE , MEDPS1 , MTDPS1 , PDECGF , hPD-ECGF Homo sapiens 10 protein-coding 2.4.2.4 131222

Summary

This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Apr 2012]

GeneOntology

Gene Loss events - TYMP (21 results)

GL_ID Species Order Gene Loss Mechanism Loss Type Lineage Specific Citation
GL_02TKNO Bos taurus Artiodactyla LOF (frameshift, premature stop, ss) Full Artiodactyla 10.1093/nargab/lqz012
GL_0FSEMT Canis lupus familiaris Carnivora LOF (frameshift, premature stop, ss) Full Carnivora 10.1093/nargab/lqz012
GL_56A29U Orcinus orca Artiodactyla LOF (frameshift, premature stop, ss) Full Artiodactyla 10.1093/nargab/lqz012
GL_6DW5GY Tursiops truncatus Artiodactyla LOF (frameshift, premature stop, ss) Full Artiodactyla 10.1093/nargab/lqz012
GL_C7W3QR Camelus bactrianus Artiodactyla LOF (frameshift, premature stop, ss) Full Artiodactyla 10.1093/nargab/lqz012
GL_CHEI4Z Bison bison Artiodactyla LOF (frameshift, premature stop, ss) Full Artiodactyla 10.1093/nargab/lqz012
GL_DJ5R9Y Manis pentadactyla Pholidota LOF (frameshift, premature stop, ss) Full No 10.1093/nargab/lqz012
GL_FC2UUU Capra hircus Artiodactyla LOF (frameshift, premature stop, ss) Full Artiodactyla 10.1093/nargab/lqz012
GL_FIPWXZ Pantholops hodgsonii Artiodactyla LOF (frameshift, premature stop, ss) Full Artiodactyla 10.1093/nargab/lqz012
GL_GBNCRH Orycteropus afer Tubulidentata LOF (frameshift, premature stop, ss) Full No 10.1093/nargab/lqz012