Reference Gene

Gene name Alias Species Exons Type Paralogs EC number OMIM
TYMP thymidine phosphorylase TP , ECGF , ECGF1 , MNGIE , MEDPS1 , MTDPS1 , PDECGF , hPD-ECGF Homo sapiens 10 protein-coding 2.4.2.4 131222

Summary

This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Apr 2012]

GeneOntology

Gene Loss events - TYMP (21 results)

GL_ID Species Order Gene Loss Mechanism Loss Type Lineage Specific Citation
GL_KBBNHK Mustela putorius furo Carnivora LOF (frameshift, premature stop, ss) Full Carnivora 10.1093/nargab/lqz012
GL_KCALSE Balaenoptera acutorostrata Artiodactyla LOF (frameshift, premature stop, ss) Full Artiodactyla 10.1093/nargab/lqz012
GL_MOT0R9 Physeter catodon Artiodactyla LOF (frameshift, premature stop, ss) Full Artiodactyla 10.1093/nargab/lqz012
GL_NEDPTX Leptonychotes weddellii Carnivora LOF (frameshift, premature stop, ss) Full Carnivora 10.1093/nargab/lqz012
GL_NUC6VD Chrysochloris asiatica Afrosoricida LOF (frameshift, premature stop, ss) Full No 10.1093/nargab/lqz012
GL_OFA6ZZ Echinops telfairi Gene deletion Full 10.1093/nargab/lqz012
GL_QJTACR Ailuropoda melanoleuca Carnivora LOF (frameshift, premature stop, ss) Full Carnivora 10.1093/nargab/lqz012
GL_SA1JZE Felis catus Carnivora LOF (frameshift, premature stop, ss) Full Carnivora 10.1093/nargab/lqz012
GL_SWQSTL Vicugna pacos Artiodactyla LOF (frameshift, premature stop, ss) Full Artiodactyla 10.1093/nargab/lqz012
GL_XJ2VXS Ursus maritimus Carnivora LOF (frameshift, premature stop, ss) Full Carnivora 10.1093/nargab/lqz012