Reference Gene

Gene name Alias Species Exons Type Paralogs EC number OMIM
ENAM enamelin ADAI , AI1C , AIH2 Homo sapiens 9 protein-coding 606585

Summary

Dental enamel forms the outer cap of teeth and is the hardest substance found in vertebrates. This gene encodes the largest protein in the enamel matrix of developing teeth. The protein is involved in the mineralization and structural organization of enamel. Defects in this gene result in amelogenesis imperfect type 1C.[provided by RefSeq, Oct 2009]

GeneOntology

Gene Loss events - ENAM (20 results)

GL_ID Species Order Gene Loss Mechanism Loss Type Lineage Specific Citation
GL_2C8CYG Bradypus tridactylus Pilosa LOF (frameshift, premature stop, ss) Full No 10.1371/journal.pgen.1000634
GL_2V2Z1H Caperea marginata Artiodactyla LOF (frameshift, premature stop, ss) Full No 10.1371/journal.pgen.1000634
GL_3L8GKQ Kogia sima Artiodactyla LOF (frameshift, premature stop, ss) Full No 10.1371/journal.pgen.1000634
GL_4GOBO4 Orycteropus afer Tubulidentata LOF (frameshift, premature stop, ss) Full No 10.1371/journal.pgen.1000634
GL_4JDXHW Eschrichtius robustus Artiodactyla LOF (frameshift, premature stop, ss) Full No 10.1371/journal.pgen.1000634
GL_5TDV36 Choloepus didactylus Pilosa LOF (frameshift, premature stop, ss) Full No 10.1371/journal.pgen.1000634
GL_6R7Q1L Tolypeutes matacus Cingulata LOF (frameshift, premature stop, ss) Full No 10.1371/journal.pgen.1000634
GL_9MINOE Eubalaena glacialis Artiodactyla LOF (frameshift, premature stop, ss) Full Eubalaena 10.1371/journal.pgen.1000634
GL_AJDDHM Kogia breviceps Artiodactyla LOF (frameshift, premature stop, ss) Full No 10.1371/journal.pgen.1000634
GL_BEDX6K Dasypus novemcinctus Cingulata LOF (frameshift, premature stop, ss) Full No 10.1371/journal.pgen.1000634