Reference Gene

Gene name Alias Species Exons Type Paralogs EC number OMIM
DRD5 dopamine receptor D5 DBDR , DRD1B , DRD1L2 Homo sapiens 1 N/a 126453

Summary

This gene encodes the D5 subtype of the dopamine receptor. The D5 subtype is a G-protein coupled receptor which stimulates adenylyl cyclase. This receptor is expressed in neurons in the limbic regions of the brain. It has a 10-fold higher affinity for dopamine than the D1 subtype. Pseudogenes related to this gene reside on chromosomes 1 and 2. [provided by RefSeq, Jul 2008]

Gene Loss events - DRD5 (14 results)

GL_ID Species Order Gene Loss Mechanism Loss Type Lineage Specific Citation
GL_1HIBRQ Balaena mysticetus Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.7717/peerj.7758
GL_AF7BUH Sousa chinensis Artiodactyla LOF (frameshift, premature stop, ss) Undetermined Cetacea 10.7717/peerj.7758
GL_AO3WWM Globicephala melas Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.7717/peerj.7758
GL_B0XMLN Physeter catodon Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.7717/peerj.7758
GL_IDZELE Lagenorhynchus obliquidens Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.7717/peerj.7758
GL_IPLUND Delphinapterus leucas Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.7717/peerj.7758
GL_J13L7F Orcinus orca Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.7717/peerj.7758
GL_LIO4ZD Lipotes vexillifer Artiodactyla LOF (frameshift, premature stop, ss) Undetermined Cetacea 10.7717/peerj.7758
GL_O770IW Eschrichtius robustus Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.7717/peerj.7758
GL_PEQXS7 Tursiops truncatus Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.7717/peerj.7758