Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| DRD5 dopamine receptor D5 | DBDR , DRD1B , DRD1L2 | Homo sapiens | 1 | N/a | 126453 |
Summary
This gene encodes the D5 subtype of the dopamine receptor. The D5 subtype is a G-protein coupled receptor which stimulates adenylyl cyclase. This receptor is expressed in neurons in the limbic regions of the brain. It has a 10-fold higher affinity for dopamine than the D1 subtype. Pseudogenes related to this gene reside on chromosomes 1 and 2. [provided by RefSeq, Jul 2008]
Gene Loss events - DRD5 (14 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_QU067Y | Neophocaena asiaeorientalis | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | Cetacea | 10.7717/peerj.7758 |
| GL_RLG366 | Ochotona princeps | Lagomorpha | LOF (frameshift, premature stop, ss) | Polymorphic | No | 10.7717/peerj.7758 |
| GL_WQLVCT | Chrysochloris asiatica | Afrosoricida | LOF (frameshift, premature stop, ss) | Full | No | 10.7717/peerj.7758 |
| GL_YOGLFI | Balaenoptera bonaerensis | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | Cetacea | 10.7717/peerj.7758 |