Ψ KRT32 - Loxodonta africana
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_YYOOWV | Loxodonta africana | Other | Full | No | Genomic & Synteny maps | XM_064270377.1 |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Functional | "Hair follicle-specific keratin genes consisted of 9 hair follicle-specific epithelial keratin genes (K71-K75, K25-K28) and 17 hair keratins (K31-K40, K81-K86) expressed in hair follicle and hair which could directly affect hair growth." | 10.1186/s12983-017-0225-x |
| Methodology & Validation | "We first identified α-keratin gene repertoires in the cow (Bos taurus) (coverage 7×,Btau_4.6.1) [...] taking all the known α-keratin gene sequences of human as queries using BLASTN and TBLASTN algorithm. [...] [Using the putative α-keratin cow genes as query,] the orthologous α-keratin genes were also scanned from the genome of [marine mammals'] terrestrial relatives, such as [...] African savanna elephant (Loxodonta africana, coverage 7×, Loxafr3.0, NCBI)." | 10.1186/s12983-017-0225-x |
Curator Observations
The authors named the keratins according to the human nomenclature. The authors describe this as a "pseudogene", and no further explanation or sequence information is provided. As such, the gene loss mechanism is inconclusive.