Functional |
"Thus, two scenarios could be put forward regarding the inactivation of Mogat3. First, it could reflect convergent skin-specific molecular changes, more specifically degeneration of SGs or changes in sebum lipid composition(Nikkari 1974)." |
10.1093/molbev/msz068 |
Functional |
"Alternatively, Mogat3 loss could be related to dietary adaptations, especially to herbivory, as in the case of T. m. latirostris, C. s. simum and L. africana." |
10.1093/molbev/msz068 |
Mutation Description |
"We identified several ORF disrupting mutations in both Dgat2l6 and Mogat3 in all of the analyzed
Cetacea. Regarding Dgat2l6, a single mutation, namely a one nucleotide deletion in exon 3, was found to be conserved across all tested species, whereas in Mogat3 several conserved mutations were identified, such as a five nucleotide insertion in exon 2, a loss of canonical 30splice site
in exon 3 (GT>GC) and the presence of a stop codon in exon 6 (fig. 2A)." |
10.1093/molbev/msz068 |