Ψ MLKL - Loxodonta africana
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_YCSECD | Loxodonta africana | Gene deletion | Undetermined | No | Genomic |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Timing of Loss | "(...) indicating that RIPK3 and MLKL were present in early stages of Afrotheria evolution, but must have been lost later in specific lineages, resulting in the existence of alternative modes of necroptosis inactivation." | 10.3389/fimmu.2021.747737 |
Curator Observations
Authors provide no details in the text and only depict this gene as absent sequence in Figure 2A.