Ψ IL20 - Physeter catodon
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_XQXBSC | Physeter catodon | LOF (frameshift, premature stop, ss) | Full | Yes | Multiple individual SRA | XM_007100344.3 |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Mutation Description | "Cetacean species IL20 gene annotation revealed the presence of several ORF disrupting mutations, of note a single transversal mutation present in all analyzed species, namely the abolition of a canonical donor splice site in exon 1 (Fig. 2a)." | 10.1007/s00251-018-1071-5 |
| Timing of Loss | "The sharing of a single conserved mutation in the donor splice site (GT>CT) of exon 1, along with the high ω rate calculated for the ancestral branch of cetaceans, suggests that IL20 pseudogenization occurred in the ancestor of whales and dolphins approximately 34 MYA (Pyenson 2017)." | 10.1007/s00251-018-1071-5 |