Ψ KRT6C - Trichechus manatus latirostris

Reference Gene:
Job_ID:
Curator:
GlossID Species Gene Loss Mechanism Loss Type Lineage Specific Evidence Accession Nr.
GL_WY8TN0 Trichechus manatus latirostris Other Full No Genomic & Synteny maps

Statements

Type Excerpt DOI
Methodology & Validation "We first identified α-keratin gene repertoires in the cow (Bos taurus) (coverage 7×,Btau_4.6.1) [...] taking all the known α-keratin gene sequences of human as queries using BLASTN and TBLASTN algorithm. [...] The putative α-keratin genes in the cow were then taken as queries to explore the α-keratin multigene family in the genome of 11 marine mammals, including [...] Florida manatee (Trichechus manatus latirostris, coverage 150×, TriManLat_1.0, NCBI)." 10.1186/s12983-017-0225-x
Phenotypic "For the fully aquatic manatee, body hairs are greatly reduced but with perioral bristles and bristle-like hairs on the oral disk that have specialized sensory and feeding function." 10.1186/s12983-017-0225-x
Other "However, some genes within one specie grouped together rather than with the members of the same family in other species, such as among the genes of K31, K33A, K33B and K34 in type I, as well as the K6A, K6B, K6C, K81, K83, K87 and K86 in the type II." 10.1186/s12983-017-0225-x

Curator Observations

The authors named the keratins according to the human nomenclature. Authors consider this gene to be a pseudogene, with no further explanation or sequence information provided. As such, the gene loss mechanism is inconclusive.