Ψ LDHC - Orcinus orca
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_U7F4MT | Orcinus orca | Exon(s) deletion | Full | Yes | Genomic | XM_004263902.3 |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Functional | "Overall, our results indicate the full dismantling of key energy-producing pathways in Odontoceti, including glycolysis, pyruvate and lactate production, mitochondrial pyruvate uptake and conversion to acetyl-CoA, and mitochondrial ketone body catabolism in the sperm cell." | 10.1016/j.cub.2021.05.062 |
| Mutation Description | "Multiple sequence alignment of the coding sequences for Bos taurus (cow), Mysticeti (baleen whales), and Odontoceti (toothed whales) emphasize the presence of disruptive mutations or exon loss (Ldhc, white rectangles; see also Figure S1 and Tables S2 and S3; figshare link in Key resources table)." | 10.1016/j.cub.2021.05.062 |
Curator Observations
See key resources table for details.