| Methodology & Validation |
"EDC genes of cetaceans were identified by comparative analysis of the region between S100A9 and S100A11 genes in the genomes of cetaceans (Supplementary Tables S2– S5; Supplementary Fig. S1–S3). " |
10.1038/s41598-021-91863-3 |
| Timing of Loss |
"Genes encoding barrier proteins such as LOR, IVL, SPRRs and CRCT1 have been conserved whereas others, such as KPRP, XP32 and most LCEs have been lost in cetaceans." |
10.1038/s41598-021-91863-3 |
| Other |
"XP32 (Skin-specific protein 32), also referred to as C1ORF68 (chromosome 1 open reading frame 68) in humans, and KPRP have been lost in cetaceans (Fig. 1)." |
10.1038/s41598-021-91863-3 |