Ψ GBA3 - Orcinus orca
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_TKLUBP | Orcinus orca | LOF (frameshift, premature stop, ss) | Full | Yes | Multiple individual SRA | XM_004266259.1 |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Mutation Description | "Gene annotation of GBA3 in Cetacea identified various ORF damaging mutations across exons 3, 4 and 5 (Fig. 1)." | 10.1038/s41598-020-68106-y |
| Timing of Loss | "Interestingly, 2 premature stop codons in exon 3 (DSLFX and YTTR X Fig. 1) were found to be conserved in all cetaceans analyzed, a strong indication that GBA3 inactivation possibly occurred in the cetacean ancestor (Supplementary Material 4)." | 10.1038/s41598-020-68106-y |