Ψ ASIC5 - Tursiops truncatus
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_SUAC7C | Tursiops truncatus | LOF (frameshift, premature stop, ss) | Full | Yes | Multiple individual SRA |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Functional | "ASIC5 is an orphan acid-sensing ion channel specifically expressed in interneuron subtypes of the vestibulocerebellum that regulates balance and eye movement (83)." | 10.1126/sciadv.aaw6671 |
| Mutation Description | "The -1 bp frameshifting deletion in exon 10 is shared between odontocetes and mysticetes and thus likely arose in the cetacean stem lineage. Exons 9 and 10 were likely later deleted in the sperm whale lineage; however, there is a small assembly gap, which is why we conservatively mark both exons as missing sequence." | 10.1126/sciadv.aaw6671 |
Curator Observations
See reference supplementary material.