Functional |
"Here we chose PKD2L1 to investigate whether cetaceans retained the sour taste modality, because mice lacking the Pkd2l1 gene have reduced sour taste ability and some people who are sour-ageusic also showed loss of the Pkd2l1 gene [38,39]." |
10.1186/s12862-014-0218-8 |
Mutation Description |
"Based on sequence alignments against cow (Bos taurus) homologues, we identified multiple ORF-disrupting indels and premature stop codons in Tas1r1, Tas1r2, Pkd2l1 and in ten Tas2rs scattered among cetacean branches." |
10.1186/s12862-014-0218-8 |
Mutation Description |
"For PKD2L1, the sole candidate sour taste receptor, we found two premature stop codons shared by all toothed whales, excluding the Dwarf sperm whale (Kogia sima) and a premature TGA stop codon shared by all cetaceans except for the baiji (Additional file 3: Figure S1)." |
10.1186/s12862-014-0218-8 |
Other |
"SEE "Additional file 3: Figures S1-S11. Indels and premature stop codons in Pkdl21, Tas1r1, Tas1r2, Tas2r1-3, Tas2r5, Tas2r16, Tas2r38-39, and Tas2r60." |
10.1186/s12862-014-0218-8 |