Ψ FAM149A - Tursiops truncatus

Reference Gene:
Job_ID:
Curator:
GlossID Species Gene Loss Mechanism Loss Type Lineage Specific Evidence Accession Nr.
GL_SKCIUH Tursiops truncatus Other Full Yes Multiple individual SRA XM_019921564.2

Statements

Type Excerpt DOI
Other "To precisely identify genes that were inactivated during the transition from land to water in the cetacean stem lineage, we made use of the recently sequenced genome of the common hippopotamus (23), a semi-aquatic mammal that, along with the pygmy hippopotamus, is the closest living relative to cetaceans, and considered only genes with no detected inactivating mutations in the hippopotamus. This resulted in a set of 85 lost genes that exhibit shared inactivating mutations in odontocetes and mysticetes, 62 (73%) of which have not been reported before (table S2)." 10.1126/sciadv.aaw6671

Curator Observations

See reference supplementary table S2. Authors do not provide details regarding the inactivating mutations identified, it is only mentioned that these mutations are conserved in odontocetes and mysticetes. NCBI annotation suggests possible coding alternative transcripts (Gene loss - To be confirmed).