Ψ IL20 - Balaenoptera acutorostrata

Reference Gene:
Job_ID:
Curator:
GlossID Species Gene Loss Mechanism Loss Type Lineage Specific Evidence Accession Nr.
GL_QQJN91 Balaenoptera acutorostrata LOF (frameshift, premature stop, ss) Full Yes Multiple individual SRA XM_057530950.1

Statements

Type Excerpt DOI
Mutation Description "Cetacean species IL20 gene annotation revealed the presence of several ORF disrupting mutations, of note a single transversal mutation present in all analyzed species, namely the abolition of a canonical donor splice site in exon 1 (Fig. 2a)." 10.1007/s00251-018-1071-5
Timing of Loss "The sharing of a single conserved mutation in the donor splice site (GT>CT) of exon 1, along with the high ω rate calculated for the ancestral branch of cetaceans, suggests that IL20 pseudogenization occurred in the ancestor of whales and dolphins approximately 34 MYA (Pyenson 2017)." 10.1007/s00251-018-1071-5