Ψ KRT26 - Physeter catodon

Reference Gene:
Job_ID:
Curator:
GlossID Species Gene Loss Mechanism Loss Type Lineage Specific Evidence Accession Nr.
GL_QJ76VV Physeter catodon LOF (frameshift, premature stop, ss) Full Yes Genomic

Statements

Type Excerpt DOI
Functional "Hair inner root sheath keratin" 10.1016/j.cub.2021.02.057
Mutation Description "The whole gene deletions in Mysticeti and Physeter obscure whether the 760-3460D in Delphinida occurred in the common ancestor of Cetacea with subsequent overprinting in Mysticeti and Physeter. Inactivation dates (Table 2) suggest that this gene was inactivated in the common ancestor of Cetacea." 10.1016/j.cub.2021.02.057
Timing of Loss "48.93 MA" 10.1016/j.cub.2021.02.057
Other "Three additional genes are inactivated in all cetaceans but are completely absent from either odontocetes (KRT2 and KRT77) or mysticetes (KRT26)." 10.1016/j.cub.2021.02.057

Curator Observations

See Table 2 for details regarding timing of loss. See Supplementary Table 2 for details regarding inactivating mutations.