Ψ HMGCS2 - Orcinus orca
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_PKR781 | Orcinus orca | LOF (frameshift, premature stop, ss) | Full | Yes | Multiple individual SRA | XM_049711658.1 |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Timing of Loss | "All 22 mutations in cetaceans were confirmed by at least 30 reads, with no support for the non-gene-inactivating allele (Figure 1B, Supplementary file 1). This includes the deletion of exon one that exhibits shared breakpoints in the toothed and baleen whale lineages (Figure 1—figure supplement 3), which strongly suggests that this deletion and thus HMGCS2 loss already occurred before the split of the main cetacean lineages (Figure 1C)." | 10.7554/eLife.38906 |