Functional |
"OMP is asingle-copygene that is strongly expressed in vertebrate OR neurons(Reisert etal.,2007), and this implies a critical role in olfaction. Functional studies and knockouts of OMP in mouse corroborate this role (Buiakova etal.,1996; Youngentob etal.,2001,2003)." |
10.1016/j.ympev.2017.01.020 |
Mutation Description |
"Inia geoffrensis (Amazon riverdolphin) has a start codon mutation (ATG to GTG), a 1-bp frameshift deletion that results in multiple premature stop codons–the earliest of which occurs at codon position 15, and a stop codon mutation (TGA toTGG)." |
10.1016/j.ympev.2017.01.020 |
Phenotypic |
"Our results favor the echolocation-priority hypothesis for the evolution of OMP in odontocetes, and further suggest that two other olfactory-specific genes, CNGA2 and CNGA4, are inactivated in some odontocetes." |
10.1016/j.ympev.2017.01.020 |