| Timing of Loss |
"Notably, the non-delphinid cetacean UCP1 primary sequences presented in the latter study show premature stop codons stemming from both nonsense and frameshift mutations (as also seen in Fig. 1), whereas the presented killer whale and bottlenose dolphin “UCP1 sequences correspond to UCP2 and UCP3, respectively. Our results further indicate that the pseudogenization of ucp1 also immediately predates strong increases in body size during the early amphibious stages of archaeocete evolution [that is, from 15- to 30-kg Himalayacetus (52.5 Ma) to 590- to 720-kg Ambulocetus/Rodhocetus (48 Ma) (50, 51)]" |
10.1126/sciadv.1602878 |