Ψ AANAT - Myrmecophaga tridactyla

Reference Gene:
Job_ID:
Curator:
GlossID Species Gene Loss Mechanism Loss Type Lineage Specific Evidence Accession Nr.
GL_NGYFIK Myrmecophaga tridactyla Exon(s) deletion Full Yes Genomic

Statements

Type Excerpt DOI
Mutation Description "On the other hand, although Yin et al. (2021) were not able to recover the genomic sequence containing the Aanat CDS in Anteaters, we uncovered, among other disruptive mutations, a conserved in-frame premature stop codon in exon 2." 10.1007/s00239-021-10025-1
Methodology & Validation "Mutational validation was performed through retrieval of raw sequencing reads in (at least) two independent Sequence Read Archive (SRA) projects (when available)." 10.1007/s00239-021-10025-1
Timing of Loss "Interestingly, the mutational profile of melatonin synthesis and signaling genes within Xenarthra, supports the occurrence of independent inactivation events among Xenarthran orders (Cingulata and Pilosa)." 10.1007/s00239-021-10025-1
Phenotypic "Our results strongly suggest a complete landscape of gene loss in Xenarthra, which further reinforce reports suggesting the lack of a pineal gland in several members of this superorder." 10.1007/s00239-021-10025-1

Curator Observations

Consult Supplementary Data 4.