Ψ PCSK9 - Erinaceus europaeus

Reference Gene:
Job_ID:
Curator:
GlossID Species Gene Loss Mechanism Loss Type Lineage Specific Evidence Accession Nr.
GL_N2PH3P Erinaceus europaeus Gene deletion Full No Genomic

Statements

Type Excerpt DOI
Mutation Description "At the other extreme were Soricidae (the common, Asian house and Indochinese shrews— Sorex araneus, Suncus murinus and Crocidura indochinensis, respectively) and the European hedgehog (Erinaceus europaeus) (Erinaceidae), where no gene remnants could be detected, either by BLAST searches against raw sequence data (even though the neighbouring BSND and USP24 gene sequences could easily be recovered) or by homology searches against the available Soricidae BSND-USP24 intergenic sequences using sequences from other Laurasiatheria species as probes (Fig. 7)." 10.1007/s10709-021-00113-x
Other "Eulipotyphla also presented a unique PCSK9 pattern: it was the order of Laurasiatheria that displayed the largest divergence among species, ranging from an apparently functional gene to the absence of recognizable gene remnants." 10.1007/s10709-021-00113-x