Ψ MTNR1A - Physeter catodon
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_LECURC | Physeter catodon | LOF (frameshift, premature stop, ss) | Full | Yes | Single individual SRA |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Mutation Description | "In Mysticeti, we were able to deduce the presence of relics of exon 1, yet presenting potentially disruptive mutations (Figure 4).For instance, in P. catodon, a 19-nucleotide deletion in exon 1 was found and validated by SRAs (Figures S11 and S12)." | 10.3390/genes10020121 |
| Phenotypic | "In fact, deletion of both Mtnr1a and Mtnr1a in mice suggested a cooperative role in the regulation of sleep/wake cycles, notably through the increase in wakefulness [11]." | 10.3390/genes10020121 |