| Functional |
"Here we chose PKD2L1 to investigate whether cetaceans retained the sour taste modality, because mice lacking the Pkd2l1 gene have reduced sour taste ability and some people who are sour-ageusic also showed loss of the Pkd2l1 gene [38,39]." |
10.1186/s12862-014-0218-8 |
| Mutation Description |
"We also found ORF-disrupting mutations in Pkd2l1 and in two bitter taste receptor genes (Tas2r3 and Tas2r60) in Hippopotamidae (Additional file 3: Figures S1-S11)." |
10.1186/s12862-014-0218-8 |
| Timing of Loss |
"For the three pseudogenized Tas2rs of Hippopotamidae, no shared ORF-disrupting mutation was found between cetaceans and Hippopotamidae, suggesting independent pseudogenization events in cetaceans and Hippopotamidae." |
10.1186/s12862-014-0218-8 |
| Other |
"SEE "Additional file 3: Figures S1-S11. Indels and premature stop codons in Pkdl21, Tas1r1, Tas1r2, Tas2r1-3, Tas2r5, Tas2r16, Tas2r38-39, and Tas2r60." |
10.1186/s12862-014-0218-8 |