Ψ PCSK9 - Hydrochoerus hydrochaeris
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_JPDTTI | Hydrochoerus hydrochaeris | LOF (frameshift, premature stop, ss) | Full | No | Genomic |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Mutation Description | "Evidence from the remaining 105 rodent species (representing 24 families) nevertheless suggests that PCSK9 pseudogenization is a rare event among rodents. Indeed, only one clear additional example was detected: the capybara (Hydrochoerus hydrochaeris), whose sequence contained a variety of nonsense and frameshift mutations (Fig. 8)." | 10.1007/s10709-021-00113-x |