Ψ KRT39 - Trichechus manatus latirostris

Reference Gene:
Job_ID:
Curator:
GlossID Species Gene Loss Mechanism Loss Type Lineage Specific Evidence Accession Nr.
GL_GJ9YVY Trichechus manatus latirostris Gene deletion Full No Genomic & Synteny maps

Statements

Type Excerpt DOI
Functional "Hair follicle-specific keratin genes consisted of 9 hair follicle-specific epithelial keratin genes (K71-K75, K25-K28) and 17 hair keratins (K31-K40, K81-K86) expressed in hair follicle and hair which could directly affect hair growth." 10.1186/s12983-017-0225-x
Methodology & Validation "We first identified α-keratin gene repertoires in the cow (Bos taurus) (coverage 7×,Btau_4.6.1) [...] taking all the known α-keratin gene sequences of human as queries using BLASTN and TBLASTN algorithm. [...] The putative α-keratin genes in the cow were then taken as queries to explore the α-keratin multigene family in the genome of 11 marine mammals, including [...] Florida manatee (Trichechus manatus latirostris, coverage 150×, TriManLat_1.0, NCBI)." 10.1186/s12983-017-0225-x
Phenotypic "For the fully aquatic manatee, body hairs are greatly reduced but with perioral bristles and bristle-like hairs on the oral disk that have specialized sensory and feeding function." 10.1186/s12983-017-0225-x
Other "[...] the manatee [α-keratin genes] still remained the comparable number (56 in manatee vs. 60 in elephant) and rate of pseudogenization (8.33% in manatee vs. 10.71% in elephant) to its terrestrial relative, i.e. elephant." 10.1186/s12983-017-0225-x

Curator Observations

The authors named the keratins according to the human nomenclature. Gene not found in genomic maps-gene deletion (Fig1).