Ψ AANAT - Physeter catodon
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_GCHCJK | Physeter catodon | LOF (frameshift, premature stop, ss) | Full | Yes | Genomic | XM_007099783.2 |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Mutation Description | "In P. catodon a unique deletion of 12 nucleotides in exon 2 was observed, which, combined with an additional 6 nucleotide deletion in exon 3, strongly suggests an inactivated ORF." | 10.3390/genes10020121 |
| Timing of Loss | "Taken together, our results strongly suggest that melatonin production and signalling is impairedin Cetacea (Figure 6). Despite the lower number of disrupting mutations found in Asmt, we still find indications of pseudogenisation in the analysed species with the exception of B. mysticetus, due to poor genome coverage. Furthermore, we were able to infer that ancestral inactivating mutations (shared between toothed and toothless whales), occurred in Mtnr1b and Aanat ORFs." | 10.3390/genes10020121 |
Curator Observations
Also reported in : M Huelsmann. 2019 [PMID:31579821].