Ψ MSS51 - Orcinus orca
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_GBVOFP | Orcinus orca | LOF (frameshift, premature stop, ss) | Full | Yes | Single individual SRA | XM_004273122.4 |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Functional | "Another example is MSS51, a gene that is predominantly expressed in fast glycolytic fibers of the skeletal muscle." | 10.1126/sciadv.aaw6671 |
| Phenotypic | "Inactivation of MSS51 in muscle cell lines directs muscle energy metabolism toward beta-oxidation of fatty acids. MSS51 was lost in the cetacean stem lineage (fig. S20 and table S2), suggesting that muscle metabolism may be largely fueled by fatty acids, which would be consistent with a high intramuscular lipid content in cetaceans." | 10.1126/sciadv.aaw6671 |
Curator Observations
See reference supplementary material.