Ψ GK2 - Tursiops truncatus

Reference Gene:
Job_ID:
Curator:
GlossID Species Gene Loss Mechanism Loss Type Lineage Specific Evidence Accession Nr.
GL_G0IIZF Tursiops truncatus LOF (frameshift, premature stop, ss) Full Yes Multiple individual SRA XM_019932668.2

Statements

Type Excerpt DOI
Mutation Description "Together, most of these metabolic steps are controlled by sperm-restricted gene orthologs, including (...) glycerol kinase 2 (Gk2), which catalyzes the production of glycerol-3-phosphate from glycerol, which can be enzymatically converted into glyceraldehyde-3-phosphate (Figure 2);23 (...) We examined each gene ortholog sequence in various mammal species and found ORF-disrupting mutations or exon-loss events in most cetacean species (Figure 2 ; figshare link in Key resources table)." 10.1016/j.cub.2021.05.062

Curator Observations

See Key Resource table for details.