| Functional |
"OMP is a single-copygene that is strongly expressed in vertebrate OR neurons(Reisert etal.,2007), and this implies a critical role in olfaction. Functional studies and knockouts of OMP in mouse corroborate this role (Buiakova etal.,1996; Youngentob etal.,2001,2003)." |
10.1016/j.ympev.2017.01.020 |
| Mutation Description |
"Among the river dolphins, Lipotes vexillifer (Yangtze River dolphin) has a 1-bp frameshift deletion that is 68bp upstream from the TGA stop codon. This deletion results in 23 unique amino acids at the carboxy-terminal end of the predicted protein plus an addition of 32amino acids that precede
the delayed stop codon." |
10.1016/j.ympev.2017.01.020 |
| Phenotypic |
"Our results favor the echolocation-priority hypothesis for the evolution of OMP in odontocetes, and further suggest that two other olfactory-specific genes, CNGA2 and CNGA4, are inactivated in some odontocetes." |
10.1016/j.ympev.2017.01.020 |