Ψ KRT6B - Ailuropoda melanoleuca
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_FVVCLF | Ailuropoda melanoleuca | Gene deletion | Full | No | Genomic & Synteny maps |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Functional | "Previous study has reported that deficient for K6B (epithelial keratins) may contributed to the absence of hair and nail in mice." | 10.1186/s12983-017-0225-x |
| Methodology & Validation | "We first identified α-keratin gene repertoires in the cow (Bos taurus) (coverage 7×,Btau_4.6.1) [...] taking all the known α-keratin gene sequences of human as queries using BLASTN and TBLASTN algorithm. [...] [Using the putative α-keratin cow genes as query,] the orthologous α-keratin genes were also scanned from the genome of [marine mammals'] terrestrial relatives, such as [...] giant panda (Ailuropoda melanoleuca, coverage 60×, AilMel_1.0, NCBI)." | 10.1186/s12983-017-0225-x |
| Other | "By contrast, [α-keratin] gene repertoires in the pinnipeds (56) and polar bear (58) were similar to that of panda (58)." | 10.1186/s12983-017-0225-x |
Curator Observations
The authors named the keratins according to the human nomenclature.