| Mutation Description |
"We report that the coding sequence of the important skin barrier gene FLG is truncated and the FLG-processing protease, caspase-14, is inactivated by mutations in the dugong." |
10.1038/s41598-024-60099-2 |
| Mutation Description |
"However, due to premature stop codons the proteins encoded by FLG, FLG2 and TCHHL1 are more than 50% shorter in sirenians than in elephants and humans (Fig. 5A, Supplementary Fig. S7)." |
10.1038/s41598-024-60099-2 |
| Other |
"Interestingly, the manatee has a potentially functional FLG including the characteristic C-terminal sequence motif of SFTPs (Fig. 5B), whereas FLG of the dugong is truncated and lacks this motif." |
10.1038/s41598-024-60099-2 |