Ψ KRT42P - Trichechus manatus latirostris

Reference Gene:
Job_ID:
Curator:
GlossID Species Gene Loss Mechanism Loss Type Lineage Specific Evidence Accession Nr.
GL_F5VRGW Trichechus manatus latirostris Other Full No Genomic & Synteny maps

Statements

Type Excerpt DOI
Methodology & Validation "We first identified α-keratin gene repertoires in the cow (Bos taurus) (coverage 7×,Btau_4.6.1) [...] taking all the known α-keratin gene sequences of human as queries using BLASTN and TBLASTN algorithm. [...] The putative α-keratin genes in the cow were then taken as queries to explore the α-keratin multigene family in the genome of 11 marine mammals, including [...] Florida manatee (Trichechus manatus latirostris, coverage 150×, TriManLat_1.0, NCBI)." 10.1186/s12983-017-0225-x
Phenotypic "For the fully aquatic manatee, body hairs are greatly reduced but with perioral bristles and bristle-like hairs on the oral disk that have specialized sensory and feeding function." 10.1186/s12983-017-0225-x
Other "[...] the manatee [α-keratin genes] still remained the comparable number (56 in manatee vs. 60 in elephant) and rate of pseudogenization (8.33% in manatee vs. 10.71% in elephant) to its terrestrial relative, i.e. elephant." 10.1186/s12983-017-0225-x

Curator Observations

The reference gene used here is a pseudogene. The authors named the keratins according to the human nomenclature. Authors consider this a "pseudogene", with no further explanation or sequence information provided. As such, the gene loss mechanism is inconclusive.