Ψ MC5R - Orycteropus afer

Reference Gene:
Job_ID:
Curator:
GlossID Species Gene Loss Mechanism Loss Type Lineage Specific Evidence Accession Nr.
GL_EMCX8R Orycteropus afer Exon(s) deletion Full No Genomic

Statements

Type Excerpt DOI
Mutation Description "For Trichechus manatus (West Indian manatee) and Orycteropus afer (aardvark), we recovered incomplete MC5R sequences that result from similar but not identical deletions in these gene sequences." 10.1016/j.ympev.2017.12.010
Mutation Description "For O. afer, a BLAST search with L. africana recovered ~220 bp at the 3' end of the coding sequence on contig 229264 (nucleotide positions 6082-6303 of ALYB01229264). Overall, the "mostly” deleted region in O. afer spans 2709 bp in L. africana although there are 187 bp in O. afer that align poorly to L. africana (Fig. 3, Supplementary Alignment File 3)." 10.1016/j.ympev.2017.12.010
Phenotypic "Inactivating mutations in MC5R also occur in aardvark and colugo, both of which have derived skin properties, i.e., thick skin in aardvarks, lack of arrector pili muscles in colugos." 10.1016/j.ympev.2017.12.010