Ψ OMP - Platanista minor

Reference Gene:
Job_ID:
Curator:
GlossID Species Gene Loss Mechanism Loss Type Lineage Specific Evidence Accession Nr.
GL_DJJSVZ Platanista minor LOF (frameshift, premature stop, ss) Full No PCR & Sanger Sequencing Multiple

Statements

Type Excerpt DOI
Functional "OMP is asingle-copygene that is strongly expressed in vertebrate OR neurons(Reisert etal.,2007), and this implies a critical role in olfaction. Functional studies and knockouts of OMP in mouse corroborate this role (Buiakova etal.,1996; Youngentob etal.,2001,2003)." 10.1016/j.ympev.2017.01.020
Mutation Description "(...)Platanista minor (Indus river dolphin) has a 2-bp frameshift deletion that results in multiple, premature stop codons, the first of which occurs at codon position 65 (Fig. 3)." 10.1016/j.ympev.2017.01.020
Phenotypic "Our results favor the echolocation-priority hypothesis for the evolution of OMP in odontocetes, and further suggest that two other olfactory-specific genes, CNGA2 and CNGA4, are inactivated in some odontocetes." 10.1016/j.ympev.2017.01.020

Curator Observations

Authors deposited isolated OMP sequences in GenBank with the following acession numbers KY496975-KY496991.